In the past week, KPTI stock has gone down by -21.53%, with a monthly gain of 14.69% and a quarterly plunge of -45.16%. The volatility ratio for the week is 13.18%, and the volatility levels for the last 30 days are 11.59% for Karyopharm Therapeutics Inc The simple moving average for the past 20 days is -17.25% for KPTI’s stock, with a -50.74% simple moving average for the past 200 days.
Is It Worth Investing in Karyopharm Therapeutics Inc (NASDAQ: KPTI) Right Now?
The 36-month beta value for KPTI is at 0.35. Analysts have varying views on the stock, with 2 analysts rating it as a “buy,” 4 rating it as “overweight,” 1 as “hold,” and 0 as “sell.”
The public float for KPTI is 7.90M, and currently, shorts hold a 25.05% of that float. The average trading volume for KPTI on May 14, 2025 was 132.10K shares.
KPTI) stock’s latest price update
Karyopharm Therapeutics Inc (NASDAQ: KPTI)’s stock price has dropped by -20.00 in relation to previous closing price of 6.15. Nevertheless, the company has seen a loss of -21.53% in its stock price over the last five trading days. benzinga.com reported 2025-05-13 that Karyopharm Therapeutics Inc. KPTI reported mixed financial results for the first quarter on Monday.
Analysts’ Opinion of KPTI
Many brokerage firms have already submitted their reports for KPTI stocks, with Piper Sandler repeating the rating for KPTI by listing it as a “Overweight.” The predicted price for KPTI in the upcoming period, according to Piper Sandler is $8 based on the research report published on January 19, 2023 of the previous year 2023.
RBC Capital Mkts, on the other hand, stated in their research note that they expect to see KPTI reach a price target of $10, previously predicting the price at $7. The rating they have provided for KPTI stocks is “Outperform” according to the report published on November 04th, 2022.
JP Morgan gave a rating of “Neutral” to KPTI, setting the target price at $8 in the report published on February 09th of the previous year.
KPTI Trading at -12.30% from the 50-Day Moving Average
After a stumble in the market that brought KPTI to its low price for the period of the last 52 weeks, the company was unable to rebound, for now settling with -72.44% of loss for the given period.
Volatility was left at 11.59%, however, over the last 30 days, the volatility rate increased by 13.18%, as shares surge +16.86% for the moving average over the last 20 days. Over the last 50 days, in opposition, the stock is trading -32.14% lower at present.
During the last 5 trading sessions, KPTI fell by -21.53%, which changed the moving average for the period of 200-days by -65.84% in comparison to the 20-day moving average, which settled at $5.95. In addition, Karyopharm Therapeutics Inc saw -51.50% in overturn over a single year, with a tendency to cut further losses.
Insider Trading
Reports are indicating that there were more than several insider trading activities at KPTI starting from Paulson Richard A., who sale 236 shares at the price of $7.12 back on May 06 ’25. After this action, Paulson Richard A. now owns 82,503 shares of Karyopharm Therapeutics Inc, valued at $1,680 using the latest closing price.
Rangwala Reshma, the EVP & Chief Medical Officer of Karyopharm Therapeutics Inc, sale 419 shares at $6.17 during a trade that took place back on Apr 23 ’25, which means that Rangwala Reshma is holding 28,853 shares at $2,585 based on the most recent closing price.
Stock Fundamentals for KPTI
Current profitability levels for the company are sitting at:
- -0.84 for the present operating margin
- 0.96 for the gross margin
The net margin for Karyopharm Therapeutics Inc stands at -0.44. The total capital return value is set at -3.19.
Based on Karyopharm Therapeutics Inc (KPTI), the company’s capital structure generated -0.8 points at debt to capital in total, while cash flow to debt ratio is standing at -1.34. The debt to equity ratio resting at -0.44. The interest coverage ratio of the stock is -5.79.
Currently, EBITDA for the company is -38.6 million with net debt to EBITDA at -1.3. When we switch over and look at the enterprise to sales, we see a ratio of 0.67. The receivables turnover for the company is 4.03for trailing twelve months and the total asset turnover is 1.11. The liquidity ratio also appears to be rather interesting for investors as it stands at 1.33.
Conclusion
In conclusion, Karyopharm Therapeutics Inc (KPTI) has had a bad performance lately. Opinion on the stock among analysts is bullish, with some giving it a “buy” rating and others a “hold”. It’s important to note that the stock is currently trading at a significant distance from its 50-day moving average and its 52-week high.
