The stock of Karyopharm Therapeutics Inc (KPTI) has seen a 35.07% increase in the past week, with a 6.61% gain in the past month, and a -42.17% decrease in the past quarter. The volatility ratio for the week is 12.21%, and the volatility levels for the past 30 days are at 12.60% for KPTI. The simple moving average for the past 20 days is 33.27% for KPTI’s stock, with a -43.09% simple moving average for the past 200 days.
Is It Worth Investing in Karyopharm Therapeutics Inc (NASDAQ: KPTI) Right Now?
Additionally, the 36-month beta value for KPTI is 0.16. There are mixed opinions on the stock, with 2 analysts rating it as a “buy,” 4 rating it as “overweight,” 1 rating it as “hold,” and 0 rating it as “sell.”
The public float for KPTI is 7.92M and currently, short sellers hold a 16.54% ratio of that float. The average trading volume of KPTI on April 25, 2025 was 124.38K shares.
KPTI) stock’s latest price update
Karyopharm Therapeutics Inc (NASDAQ: KPTI)’s stock price has dropped by -4.78 in relation to previous closing price of 6.27. Nevertheless, the company has seen a gain of 35.07% in its stock price over the last five trading days. prnewswire.com reported 2025-04-01 that NEWTON, Mass., April 1, 2025 /PRNewswire/ — Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 1,850 restricted stock units (RSUs) to two newly-hired employees.
Analysts’ Opinion of KPTI
Many brokerage firms have already submitted their reports for KPTI stocks, with Piper Sandler repeating the rating for KPTI by listing it as a “Overweight.” The predicted price for KPTI in the upcoming period, according to Piper Sandler is $8 based on the research report published on January 19, 2023 of the previous year 2023.
RBC Capital Mkts, on the other hand, stated in their research note that they expect to see KPTI reach a price target of $10, previously predicting the price at $7. The rating they have provided for KPTI stocks is “Outperform” according to the report published on November 04th, 2022.
JP Morgan gave a rating of “Neutral” to KPTI, setting the target price at $8 in the report published on February 09th of the previous year.
KPTI Trading at -4.79% from the 50-Day Moving Average
After a stumble in the market that brought KPTI to its low price for the period of the last 52 weeks, the company was unable to rebound, for now settling with -66.83% of loss for the given period.
Volatility was left at 12.60%, however, over the last 30 days, the volatility rate increased by 12.21%, as shares surge +23.09% for the moving average over the last 20 days. Over the last 50 days, in opposition, the stock is trading -33.46% lower at present.
During the last 5 trading sessions, KPTI rose by +35.07%, which changed the moving average for the period of 200-days by -49.63% in comparison to the 20-day moving average, which settled at $4.48. In addition, Karyopharm Therapeutics Inc saw -41.15% in overturn over a single year, with a tendency to cut further losses.
Insider Trading
Reports are indicating that there were more than several insider trading activities at KPTI starting from Rangwala Reshma, who sale 419 shares at the price of $6.17 back on Apr 23 ’25. After this action, Rangwala Reshma now owns 28,853 shares of Karyopharm Therapeutics Inc, valued at $2,585 using the latest closing price.
Paulson Richard A., the President and CEO of Karyopharm Therapeutics Inc, sale 245 shares at $3.74 during a trade that took place back on Apr 04 ’25, which means that Paulson Richard A. is holding 82,739 shares at $916 based on the most recent closing price.
Stock Fundamentals for KPTI
Current profitability levels for the company are sitting at:
- -0.82 for the present operating margin
- 0.96 for the gross margin
The net margin for Karyopharm Therapeutics Inc stands at -0.53. The total capital return value is set at -1.66.
Based on Karyopharm Therapeutics Inc (KPTI), the company’s capital structure generated 22.87 points at debt to capital in total, while cash flow to debt ratio is standing at -0.66. The debt to equity ratio resting at -1.05. The interest coverage ratio of the stock is -3.19.
Currently, EBITDA for the company is -38.6 million with net debt to EBITDA at -3.42. When we switch over and look at the enterprise to sales, we see a ratio of 1.26. The receivables turnover for the company is 4.72for trailing twelve months and the total asset turnover is 0.88. The liquidity ratio also appears to be rather interesting for investors as it stands at 1.70.
Conclusion
In conclusion, Karyopharm Therapeutics Inc (KPTI) has seen mixed performance in recent times. Analysts have a bullish opinion on the stock, with some rating it as a “buy” and others rating it as a “hold”. It’s important to note that the stock is currently trading at a significant distance from its 50-day moving average and its 52-week high.
