Sionna Therapeutics Inc (SION) Stock: A Value Analysis

Analysts have varying opinions on the stock, with 3 analysts rating it as a “buy,” 0 as “overweight,” 0 as “hold,” and 0 as “sell.”

The public float for SION is 27.05M and currently, short sellers hold a 4.91% of that float. On March 25, 2025, SION’s average trading volume was 293.74K shares.

SION) stock’s latest price update

Sionna Therapeutics Inc (NASDAQ: SION)’s stock price has decreased by -11.61 compared to its previous closing price of 13.69. However, the company has seen a -18.74% decrease in its stock price over the last five trading sessions. globenewswire.com reported 2025-03-20 that Phase 1 MAD dosing completed for SION-451 and final MAD cohort of SION-719 planned; Interim data in healthy volunteers show potential to provide clinically meaningful benefit to CF patients. Topline data anticipated in first half of 2025

SION’s Market Performance

The volatility ratio for the week is 14.38%, and the volatility levels for the past 30 days are at 14.95% for SION. The simple moving average for the past 20 days is -19.83% for SION’s stock, with a -29.13% simple moving average for the past 200 days.

Analysts’ Opinion of SION

Stifel, on the other hand, stated in their research note that they expect to see SION reach a price target of $32. The rating they have provided for SION stocks is “Buy” according to the report published on March 04th, 2025.

Guggenheim gave a rating of “Buy” to SION, setting the target price at $45 in the report published on March 04th of the current year.

SION Trading at -29.13% from the 50-Day Moving Average

After a stumble in the market that brought SION to its low price for the period of the last 52 weeks, the company was unable to rebound, for now settling with -51.97% of loss for the given period.

Volatility was left at 14.95%, however, over the last 30 days, the volatility rate increased by 14.38%, as shares sank -38.59% for the moving average over the last 20 days.

During the last 5 trading sessions, SION fell by -18.74%, in comparison to the 20-day moving average, which settled at $15.09. In addition, Sionna Therapeutics Inc saw -51.60% in overturn over a single year, with a tendency to cut further losses.

Insider Trading

Reports are indicating that there were more than several insider trading activities at SION starting from TPG GP A, LLC, who purchase 1,125,000 shares at the price of $18.00 back on Feb 10 ’25. After this action, TPG GP A, LLC now owns 6,684,962 shares of Sionna Therapeutics Inc, valued at $20,250,000 using the latest closing price.

RA CAPITAL MANAGEMENT, L.P., the Director of Sionna Therapeutics Inc, purchase 1,125,000 shares at $18.00 during a trade that took place back on Feb 10 ’25, which means that RA CAPITAL MANAGEMENT, L.P. is holding 6,923,365 shares at $20,250,000 based on the most recent closing price.

Stock Fundamentals for SION

The liquidity ratio also appears to be rather interesting for investors as it stands at 14.49.

Conclusion

To wrap up, the performance of Sionna Therapeutics Inc (SION) has been bad in recent times. The stock has received a bullish of “buy” and “hold” ratings from analysts. It’s important to note that the stock is currently trading at a significant distance from its 50-day moving average and its 52-week high.

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